The institution was founded in 1883 as Cleff Hall and was absorbed into the Devoner University system in 1906. The main campus of Devoner University is located elsewhere in the city, in the neighborhood of East Kempton.
A portion of the school was damaged beyond repair in the 2015 Crestman Hospital attack. A new extension to Cleff Hall to replace the destroyed portion was constructed and opened as the Paddleford Center in January 2017.
The building was added to the Adustelan Register of Historic Places on January 4, 2017.